Hydrophilic matrices to be used as bioactive and degradable bone cements

OsteoInk: Bioactive Bone Cements

Incorporation of r-Amylase Enzyme and a Bioactive Filler into Hydrophilic, Partially Degradable, and Bioactive Cements (HDBCs) as a New Approach To Tailor Simultaneously Their Degradation and Bioactive Behavior

Hydrophilic, partially degradable, and bioactive cements (HDBCs) are starch-containing cements intended to degrade partially in the human body and, in so doing, allow for bone ingrowth inside the pores formed during degradation. Therefore, the study of degradation and bioactivity behavior was performed to assess the suitability of the current HDBCs formulations to achieve those aims. The degrad...

Bactericidal strontium-releasing injectable bone cements based on bioactive glasses.

Strontium-releasing injectable bone cements may have the potential to prevent implant-related infections through the bactericidal action of strontium, while enhancing bone formation in patients suffering from osteoporosis. A melt-derived bioactive glass (BG) series (SiO2–CaO–CaF2–MgO) with 0–50% of calcium substituted with strontium on a molar base were produced. By mixing glass powder, poly(ac...

Prepration and Characterization of Novel Ionoic Polymers to be Used as Artificial Muscles

      The muscle-like technology would be of enormous advantages for biomedical applications such as medical implants and human assist devices. Ionic polymer metal composites (IPMCs) are one kind of biomimetic actuators. An ionic polymer metal composite composed from an ionomer with high ion exchange capacity that packed between two thin metal layers. In the present study we focused on the prep...

Fiber reinforced calcium phosphate cements -- on the way to degradable load bearing bone substitutes?

Calcium phosphate cements (CPC) are well-established materials for the repair of bone defects with excellent biocompatibility and bioactivity. However, brittleness and low flexural/tensile strength so far restrict their application to non-load bearing areas. Reinforcement of CPC with fibers can substantially improve its strength and toughness and has been one major strategy to overcome the pres...